Medical Drug Question - i know there are some specialists here

[Mike Dziubina]

I know there are some doc's on here so just looking for some help if possible. I have a presentation due Wednesday for pharmacology. I was assigned to do this NME for 2009 called Savella (Milnacipran), it is a SNRI used to treat depression and fibromyalgia, for my report it is geared more towards FM. I understand it is a re uptake inhibitor of Norepinephrine and serotonin but what i am confused about is how this in turn helps deal with the "pain signal" with FM. by blocking the receptor on the presynaptic terminal, you are increasing synaptic cleft levels of Serotonin and NorE. how does this help with FM? is it because there are MAO and COMT in the cleft which breakdown the NTMs and limit presynaptic levels of the NTMs??? thank you guys i appreciate it.

 

[Bill Barber]

Sorta works like Stabil works with gasolene me thinks J/K

TJR will have the correct answere for you shortly:lol:

 

[Nelson Atwell]

Bill, I think Caymen will pipe in too. :lol:

 

[Thomas Rogers]

Mike CT,



I'll do your pharmacology work for you if you take up the slack I have in defining industry meta-data standard for the CableLabs Asset Distribution Interface (ADI) 3.0, used by cable operators and digital video content providers for packaging, describing and distributing next-generation digital video assets. I'm behind the eight-ball and have about 20 pages of XML schema definition documentation to write by noon Wed.



TJR

 

[gary s]

just give me some "ludes" and i will be fine :lol:

 

[Mike Dziubina]

Disregard -



got what i need. thanks.

 

[EddieS'04]

just give me some "ludes" and i will be fine

Wow Gary, that was many years ago....LOL

 

[Gavin Allan]

Got any medical maryjane?

 

[gary s]

eddie,



i am glad someone picked up that reference. boy are we getting old :lol:

 

[Bill Barber]

Mid 70s to be exact.

 

[gary s]

ok old timers,



what was the # stamped on the "lude" ?

disclaimer: not that i would know. a friend wants to know :lol:

 

[Bill Barber]

Depends on the dosage, As I recall the caps are light blue , 300 would be 300 MGs.

been almost 40 yrs.

 

[Robert Caffyn]

714... did enough to know. They were in tablet form, never came in a capsule. :wacko:

 

[Bill Barber]

They most certainly did in in caps, In USP legal form, was not just a street drug, was also a prescribed legal med.

 

[EddieS'04]

714, only saw tabs here.

 

[Robert Caffyn]

Whoa, I only saw them in tablets and when I went into the medical field that was one habit that didn't come with me. By then I could have cared less about any of the "dry goods" I did in my youth. So if you say they did, so be it.

 

[Bill Barber]

google pics of ludes.

 

[Robert Caffyn]

Thanks Bill, you certianly have a plethora of knowledge in that little head of yours. Like I said, who cares?